Dr. Dean Betts
Professor, Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry
Canine Pluripotent Stem Cells – Progress, Hurdles and Opportunities
Monday, September 9, 9:30 AM – 10:00 AM
The derivation of canine embryonic stem cells (cESCs) and generation of canine induced pluripotent stem cells (ciPSCs) are significant achievements that have unlocked the potential for developing novel cell-based disease models, drug discovery platforms, and transplantation therapies in the dog. A progression from concept to cure in this clinically-relevant companion animal will not only help our canine patients but also help advance human regenerative medicine. Nevertheless, many issues remain to be resolved before pluripotent stem cells can be used clinically in a safe and reproducible manner. In this seminar, an up-to-date progress in the canine pluripotent stem cell field will be reported along with presenting the current obstacles and ideas to overcome these hurdles to progress these cells from the laboratory to the clinic.